Management of Thrombocytopenia with Partial Splenic Embolization in Liver Cirrhosis

Authors

  • Septia Harma Putri Department of Gastroenterohepatology, Faculty of Medicine, Universitas Andalas/Dr. M. Djamil General Hospital, Padang, Indonesia
  • Arnelis Department of Gastroenterohepatology, Faculty of Medicine, Universitas Andalas/Dr. M. Djamil General Hospital, Padang, Indonesia
  • Saptino Miro Department of Gastroenterohepatology, Faculty of Medicine, Universitas Andalas/Dr. M. Djamil General Hospital, Padang, Indonesia

DOI:

https://doi.org/10.37275/bsm.v8i6.1015

Keywords:

Liver cirrhosis, Partial splenic embolization, Thrombocytopenia

Abstract

Thrombocytopenia is a frequent complication in patients with cirrhosis. Thrombocytopenia is generally divided into mild, moderate, and severe thrombocytopenia. Thrombocytopenia in liver cirrhosis not only increases the risk of bleeding during surgery but can also have an impact on patient management, such as liver biopsy, administration of antiviral therapy, and postponement of elective surgery. The pathophysiology of thrombocytopenia in chronic liver disease can be caused by decreased platelet production, sequestration in the spleen, and increased platelet destruction. Partial splenic embolization (PSE) is one option for treating thrombocytopenia in chronic liver disease. PSE is an effective procedure in treating complications associated with hypersplenism and portal hypertension, such as esophageal varices, pancytopenia, portal hypertensive gastropathy and ascites.

Authors

  • Septia Harma Putri1*
  • Arnelis1
  • Saptino Miro1
  1. 1Department of Gastroenterohepatology, Faculty of Medicine, Universitas Andalas/Dr. M. Djamil General Hospital, Padang, Indonesia

Corresponding author Septia Harma Putri — septiaharmaputri@gmail.com

Article history

  1. Submitted
  2. Accepted
  3. Published

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Published

2024-04-03

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How to Cite

1.
Putri SH, Arnelis, Saptino Miro. Management of Thrombocytopenia with Partial Splenic Embolization in Liver Cirrhosis. Bioscmed [Internet]. 2024 Apr. 3 [cited 2026 Aug. 12];8(6):4519-28. Available from: https://bioscmed.com/index.php/bsm/article/view/1015

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