A Rare Primary Breast Angiosarcoma with Bone Metastasis: A Case Report
DOI:
https://doi.org/10.37275/bsm.v8i10.1095Keywords:
Angiosarcoma, Bone metastasis, Breast cancer, Case report, Rare tumorAbstract
Background: Angiosarcoma is a rare and aggressive malignant tumor originating from endothelial cells. Primary breast angiosarcoma (PBA) is exceedingly uncommon, accounting for less than 1% of all breast malignancies. Bone metastasis from PBA is even rarer, making it a unique clinical entity.
Case presentation: We present the case of a 37-year-old woman who initially presented with a rapidly enlarging breast mass. A biopsy confirmed the diagnosis of PBA, and she underwent a modified radical mastectomy followed by radiotherapy. Seventeen months later, she developed progressive lower extremity weakness and urinary and bowel incontinence. Imaging revealed a spinal metastasis at the Th4-Th6 level. Biopsy and immunohistochemistry confirmed metastatic angiosarcoma. The patient underwent laminectomy and posterior stabilization.
Conclusion: This case highlights the rarity and aggressive nature of PBA with bone metastasis. It emphasizes the importance of early detection, comprehensive treatment, and long-term surveillance in managing this challenging disease. Further research is needed to understand the underlying mechanisms and develop effective therapeutic strategies for PBA with bone metastasis.
Authors
- Rupita Sari 1*
- Kiki A. Rizki2
- Anglita Yantisetiasti3
- 1Trainee of Oncology Surgery, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia
- 2Division of Oncology Surgery, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia
- 3Division of Anatomical Pathology, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia
Corresponding author Rupita Sari — rupita.sitanggang@gmail.com
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