Beyond Infection: The Role of Stunting in Tuberculosis Susceptibility and Treatment Outcomes
DOI:
https://doi.org/10.37275/bsm.v9i2.1202Keywords:
Immunity, Infection, Malnutrition, Stunting, TuberculosisAbstract
Background: Tuberculosis (TB) remains a major global health concern, particularly in developing countries. Stunting, a manifestation of chronic malnutrition, is prevalent in these regions and is increasingly recognized as a significant risk factor for TB. This systematic review aims to comprehensively analyze the impact of stunting on TB susceptibility and treatment outcomes.
Methods: A systematic search of PubMed and ScienceDirect databases was conducted for studies published in the last 10 years, focusing on the relationship between stunting and TB. The PRISMA guidelines were followed for article selection and data extraction.
Results: The review identified a significant association between stunting and increased TB risk. Stunted individuals exhibit impaired immune responses, making them more susceptible to TB infection. Moreover, stunting negatively affects TB treatment outcomes, including increased treatment duration, higher relapse rates, and greater mortality risk.
Conclusion: Stunting is a critical determinant of TB susceptibility and treatment outcomes. Addressing stunting through comprehensive nutritional interventions is crucial not only for reducing the burden of malnutrition but also for enhancing TB prevention and control efforts.
Authors
- Deddy Herman1*
- Delmi Sulastri2
- 1Department of Pulmonology and Respiratory Medicine, Doctoral Programme in Public Health, Faculty of Medicine, Universitas Andalas, Padang, Indonesia
- 2Department of Nutrition, Faculty of Medicine, Universitas Andalas, Padang, Indonesia
Corresponding author Deddy Herman — deddykaterine@gmail.com
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