A Rare Case of Systemic Lupus Erythematosus with Concomitant Inflammatory Bowel Disease: A Diagnostic and Therapeutic Challenge

Authors

  • Made Cantika Kumara Dipa Department of Internal Medicine, Wangaya Regional Hospital, Denpasar, Indonesia
  • Ketut Suryana Department of Internal Medicine, Wangaya Regional Hospital, Denpasar, Indonesia

DOI:

https://doi.org/10.37275/bsm.v9i4.1248

Keywords:

Autoimmune disease, Crohn's disease, Inflammatory bowel disease, Systemic lupus erythematosus, Ulcerative colitis

Abstract

Background: Systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD) are chronic conditions with complex pathophysiologies. While both diseases can affect the gastrointestinal tract, their co-occurrence is rare and presents unique diagnostic and therapeutic challenges. This case report describes a patient with SLE who developed IBD, highlighting the complexities of managing such cases.

Case presentation: A 27-year-old female with a history of SLE presented with hematochezia, abdominal pain, and weight loss. A colonoscopy revealed findings consistent with IBD. The patient's SLE was well-controlled on immunosuppressive therapy, but the addition of IBD required careful medication adjustments to manage both conditions effectively.

Conclusion: The coexistence of SLE and IBD is an uncommon but significant clinical scenario. This case underscores the importance of a thorough evaluation of IBD in SLE patients presenting with gastrointestinal symptoms. Furthermore, it emphasizes the need for a multidisciplinary approach to optimize treatment strategies and improve patient outcomes.

Authors

  • Made Cantika Kumara Dipa1*
  • Ketut Suryana1
  1. 1Department of Internal Medicine, Wangaya Regional Hospital, Denpasar, Indonesia

Corresponding author Made Cantika Kumara Dipa — madecantikakumaradipa@gmail.com

Article history

  1. Submitted
  2. Accepted
  3. Published

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Published

2025-01-24

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How to Cite

1.
Made Cantika Kumara Dipa, Ketut Suryana. A Rare Case of Systemic Lupus Erythematosus with Concomitant Inflammatory Bowel Disease: A Diagnostic and Therapeutic Challenge. Bioscmed [Internet]. 2025 Jan. 24 [cited 2026 Aug. 12];9(4):1128-40. Available from: https://bioscmed.com/index.php/bsm/article/view/1248