Six-Minute Walk Test Performance in Non-Dialysis Chronic Kidney Disease: An Observational Study from a Tertiary Hospital Setting
DOI:
https://doi.org/10.37275/bsm.v9i7.1324Keywords:
Chronic kidney disease, Functional capacity, Metabolic equivalents (METs), Non-dialysis, Six-minute walk testAbstract
Background: Functional capacity dramatically declines in non-dialysis chronic kidney disease (CKD-ND), impacting patient prognosis and quality of life. Accurate, practical assessment is crucial for timely intervention. This study evaluated functional capacity using Six-Minute Walk Test (6MWT) and explored associated clinical factors in Indonesian CKD-ND patients.
Methods: We conducted a cross-sectional study at RSUP Dr. M. Djamil Padang, enrolling 44 patients with CKD stages 3-5 not on dialysis. Using purposive sampling, we collected 6MWT distance (6MWD) following ATS guidelines and extracted demographic/clinical data (age, gender, BMI, eGFR, etiology) from medical records. Functional capacity, expressed as Metabolic Equivalents (METs), was estimated from 6MWD and patient data using the Nury formula. Descriptive statistics summarized the findings.
Results: The cohort (54.5% male, mean age 56-65 years) predominantly had advanced CKD (43.2% Stage 5) and hypertension etiology (45.4%). Functional capacity was severely impaired: mean 6MWD was low (Men: 291m, Women: 255m), and a striking 70.5% of patients exhibited low functional capacity (<3.0 METs). No participants achieved high capacity (>6.0 METs). Lower mean 6MWD and a higher prevalence of low METs were distinctly observed in patients with lower eGFR and advanced age.
Conclusion: This study reveals profound functional limitations in Indonesian CKD-ND patients well before dialysis initiation. Lower eGFR and older age were strongly associated with poorer performance. The 6MWT effectively quantifies this impairment, highlighting its utility for routine screening and emphasizing the urgent need for functional assessment and rehabilitation strategies in CKD-ND management.
Authors
- Irena Fathin Amelia1
- Harnavi Harun2*
- Miftah Irramah3
- Selfi Renita Rusjdi4
- 1Faculty of Medicine, Universitas Andalas, Padang, Indonesia
- 2Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Andalas/Dr. M. Djamil General Hospital, Padang, Indonesia
- 3Department of Physiology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia
- 4Department of Parasitology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia
Corresponding author Harnavi Harun — harnavi@med.unand.ac.id
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