Graft Outcome of Corneal Patch for Perforated Corneal Ulcer

Authors

  • Apriwan D Department of Ophthalmology, Faculty of Medicine, Universitas Andalas/Dr. M. Djamil General Hospital, Padang, Indonesia
  • Vitresia H Department of Ophthalmology, Faculty of Medicine, Universitas Andalas/Dr. M. Djamil General Hospital, Padang, Indonesia
  • Anggraini R Padang Eye Centre Hospital, Padang, Indonesia

DOI:

https://doi.org/10.37275/bsm.v7i3.797

Keywords:

Anterior chamber depth, Corneal patch graft, Perforated corneal ulcer

Abstract

Background: Corneal patch graft (CPG) is a part of the tectonic penetrating keratoplasty procedure performed on the perforated corneal ulcer. This procedure involves filling affected areas with full or partial-thickness cornea donors. This study aimed to determine the clinical results of corneal patch grafts in perforated corneal ulcers.

Methods: A retrospective study assessing clinical results of CPG on the perforated corneal ulcer with iris prolapse. Clinical assessments include graft condition, anterior chamber depth (ACD), and visual acuity after surgery, with a follow-up duration of up to 8 weeks.

Results: Twenty-one cases of perforated corneal ulcer with iris prolapse in 15 males (71.4%) and 6 females (28.6%). Locations of ulcer are peripheral and paracentral corneal. Visual acuity showed around light perception (LP) to 0.4. The most common etiology for corneal ulcers was infection (88.9%), followed by non-infection (Mooren’s ulcer) (11.1%). The graft condition after surgery showed promising results in 18 cases (85.7%), infection in 1 case (4.8%), and melting in 2 cases (9.5%). Adequate ACD was obtained in 77.8% of cases. An increase in visual acuity was shown in 44.4% of cases, depending on the location and severity of the ulcer.

Conclusion: A corneal patch graft is an appropriate choice in treating perforated corneal ulcers to maintain ocular integrity (tectonic keratoplasty). However, in non-infectious ulcers, this procedure has not shown a good result, which may be related to disease progressivity.

Authors

  • Apriwan D1*
  • Vitresia H1
  • Anggraini R2
  1. 1Department of Ophthalmology, Faculty of Medicine, Universitas Andalas/Dr. M. Djamil General Hospital, Padang, Indonesia
  2. 2Padang Eye Centre Hospital, Padang, Indonesia

Corresponding author Apriwan D — dikiapriwan@gmail.com

Article history

  1. Submitted
  2. Accepted
  3. Published

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Published

2023-05-05

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How to Cite

1.
D A, Vitresia H, Anggraini R. Graft Outcome of Corneal Patch for Perforated Corneal Ulcer. Bioscmed [Internet]. 2023 May 5 [cited 2026 Aug. 12];7(3):3216-20. Available from: https://bioscmed.com/index.php/bsm/article/view/797