Article Sidebar
Main Article Content
Abstract
Background: The use of Pipelle sampling for endometrial histology and pathology is of some controversy - and vast importance. Pipelle procedures are performed commonly in medical offices when women show abnormal vaginal bleeding. While the method has several advantages over dilatation and curettage (D&C), clinical questions exist on the precision and accuracy of the procedure. This study aimed to assess the effectiveness of Pipelle biopsy sampling versus Dilatation & Curettage (D&C) in adequacy of sampling specimen in terms of cost effectiveness, diagnosis success rate, sensitivity, specificity, positive predictive value, and negative predictive value.
Methods: A retrospective study was conducted among all enrolled women with abnormal uterine bleeding counselling outpatient and inpatient in MMMHMC Batac from 2016 to 2017. Sample was divided in two groups - those that underwent Pipelle biopsy and those who underwent D&C. Key statistics were computed using SPSS 16.
Results: Cost effectiveness analysis showed that Pipelle biopsy offers a more cost effective alternative with an estimate of one correct diagnosis every P16 spent versus P61 spent for a correct diagnosis using D&C. Both procedures resulted in a 100% likelihood ratio of having the condition with a positive test result, with D&C resulting in a higher diagnosis success rate of 98% (versus 92% for Pipelle) and higher proportion of those who have the disorder, given the procedure tested positive.
Conclusion: Pipelle biopsy offers a more cost effective alternative to D&C. Both procedures resulted in equal probability of having the condition with a positive test result, with D&C resulting in a higher success rate of diagnosis and sensitivity rate, albeit not statistically significant.
Keywords
Article Details
As our aim is to disseminate original research article, hence the publishing right is a necessary one. The publishing right is needed in order to reach the agreement between the author and publisher. As the journal is fully open access, the authors will sign an exclusive license agreement.
The authors have the right to:
- Share their article in the same ways permitted to third parties under the relevant user license.
- Retain copyright, patent, trademark and other intellectual property rights including research data.
- Proper attribution and credit for the published work.
For the open access article, the publisher is granted to the following right.
- The non-exclusive right to publish the article and grant right to others.
- For the published article, the publisher applied for the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
