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Abstract

Idiopathic pulmonary fibrosis is a chronic progressive interstitial lung disease (ILD) with unknown causes. Male gender, age > 60 years, history of smoking with symptoms of dry cough and progressive chronic shortness of breath are typical clinical findings in this patient. The diagnosis is made based on a combination of radiological findings in the form of a pattern consistent with usual interstitial pneumonia (UIP) and/or histopathology with the exclusion of other causes of ILD. Treatment includes pharmacological and non-pharmacological therapy in the form of pulmonary rehabilitation, psychosocial support, and lung transplantation. Anti-fibrosis pharmacological therapy, namely nintedanib and pirfenidone, has been proven to slow the progression of pulmonary fibrosis and reduce mortality. The relatively low average survival rate of 3-4 years after the diagnosis is made makes this disease have a poor prognosis and requires adequate identification and treatment in order to reduce morbidity, mortality and improve the quality of life of sufferers.

Keywords

Antifibrosis Idiopathic pulmonary fibrosis Usual interstitial pneumonia

Article Details

How to Cite
Febrina, N., & Dewi Wijaya. (2024). Idiopathic Pulmonary Fibrosis: A Narrative Literature Review. Bioscientia Medicina : Journal of Biomedicine and Translational Research, 8(8), 4769-4780. https://doi.org/10.37275/bsm.v8i8.1052