Article Sidebar
Main Article Content
Abstract
ABSTRACT
Malaria is one of the spread-disease that become a global public health problem included Indonesia. One of the controlling approach of vector-borne disease is by avoiding direct contact of human and mosquitoes. Natural insecticide is an alternative method that can be used. Carica papaya L. is one of the natural insecticide because contains of alkaloid, flavonoid and saponin. This research was aimed to determine the activity of active fraction. was a quasi-experiment research with post test only group design. This research was conducted in April – June 2017. Extraction and fractination was performed in laboratory of MIPA Biologi of Sriwijaya University. The experiment was performed in laboratory of Entomologi Baturaja. The sample of the research was Anopheles sp. larva instar III and IV. Larvacide test used 6 different concentrations which was 0,125%, 0,25%, 0,5%, 1,0% and 2,0% with aquadest as a control. Anova test and post hoc analysis with SPSS 22 software. The result of efficacy test to Anopheles sp. larva showed that N-hexan was the fraction with highest larvacide ability that kill 95% larva at 2% concentration level. Thin layer chromatography test showed a compound of Terpenoid. Activity test of active fraction N-heksan of papaya leaf with the highest mortality rate 92,5% and the lowest 46,25%. LC50 fraction N-heksan of papaya leaf was high toxicity at 24 hours of observation. Anova test showed there was significant influence and difference of various concentration of active fraction of papaya leaf to the mortality of Anopheles sp. larva with p value < α (0,00<0,05).
Key words : Anopheles sp. larva, N-hexan fraction of papaya leaf, larvacide
Article Details
As our aim is to disseminate original research article, hence the publishing right is a necessary one. The publishing right is needed in order to reach the agreement between the author and publisher. As the journal is fully open access, the authors will sign an exclusive license agreement.
The authors have the right to:
- Share their article in the same ways permitted to third parties under the relevant user license.
- Retain copyright, patent, trademark and other intellectual property rights including research data.
- Proper attribution and credit for the published work.
For the open access article, the publisher is granted to the following right.
- The non-exclusive right to publish the article and grant right to others.
- For the published article, the publisher applied for the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
