Tear Reservoir Thickness and Vector-Resolved Refractive Outcomes in Indonesian Corneal Ectasia: A Scleral Lens Pilot Study

Authors

  • Anak Agung Ayu Putri Prematura Sri Anasary Department of Ophthalmology, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia
  • Ariesanti Tri Handayani Department of Ophthalmology, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia

DOI:

https://doi.org/10.37275/bsm.v10i2.1512

Keywords:

Corneal ectasia, Physiological optics, Scleral lenses, Tear reservoir, Vector analysis

Abstract

Background: Corneal ectasia is characterized by high-order aberrations and irregular astigmatism, presenting significant optical challenges. Scleral lenses neutralize these irregularities via a post-lens tear reservoir. However, the precise optical contribution of the tear reservoir thickness itself to residual refractive error remains under-characterized, particularly in Southeast Asian populations where aggressive ectasia phenotypes are common. This study aimed to determine if tear reservoir thickness correlates with residual refractive error using vector analysis.

Methods: This retrospective pilot study analyzed 12 eyes of 8 patients with severe corneal ectasia fitted with scleral lenses in Indonesia. Refractive outcomes were converted to Thibos power vectors (M, J0, J45). To account for bilateral eye correlations, linear mixed models (LMM) were employed with Patient ID as a random effect. A theoretical thick-lens model compared predicted versus observed over-refraction.

Results: The cohort (mean age 28 ± 10.2 years) achieved significant visual improvement (LogMAR 0.35 to 0.17; p = 0.005). The mean tear reservoir thickness was 263.33 ± 80.92 μm. LMM analysis revealed no statistically significant correlation between fluid thickness and Spherical Equivalent (M) (beta = -0.001, p = 0.72) or Blur Strength (p = 0.68). The theoretical model indicated that residual error was driven by uncorrected posterior corneal astigmatism rather than fluid depth.

Conclusion: In this Indonesian cohort, optical efficacy was driven by refractive index matching at the corneal interface, not reservoir thickness. Clinical fitting should prioritize physiological clearance over refractive manipulation.

Authors

  • Anak Agung Ayu Putri Prematura Sri Anasary1*
  • Ariesanti Tri Handayani1
  1. 1Department of Ophthalmology, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia

Corresponding author Anak Agung Ayu Putri Prematura Sri Anasary — prematuraa@gmail.com

Article history

  1. Submitted
  2. Accepted
  3. Published

Downloads

Published

2025-12-05

Article metrics

264Abstract views
175PDF downloads

How to Cite

1.
Anak Agung Ayu Putri Prematura Sri Anasary, Ariesanti Tri Handayani. Tear Reservoir Thickness and Vector-Resolved Refractive Outcomes in Indonesian Corneal Ectasia: A Scleral Lens Pilot Study. Bioscmed [Internet]. 2025 Dec. 5 [cited 2026 Aug. 13];10(2):546-58. Available from: https://bioscmed.com/index.php/bsm/article/view/1512

Most read articles by the same author(s)