Factors Affecting Bisphosphonate Therapy Compliance In Patients With Osteogenesis Imperfecta

Authors

  • Yoyos Ismiarto a:1:{s:5:"en_US";s:16:"RS Hasan Sadikin";}
  • Firdaus Ramli F Resident of Orthopaedic and Traumatology, RS Hasan Sadikin, UNPAD, Bandung
  • Doddi Putra Pratama Sudjana Resident of Orthopaedic and Traumatology, RS Hasan Sadikin, UNPAD, Bandung
  • Naufal Chairulfatah Resident of Orthopaedic and Traumatology, RS Hasan Sadikin, UNPAD, Bandung
  • Wendy Yolanda Rossa Resident of Orthopaedic and Traumatology, RS Hasan Sadikin, UNPAD, Bandung

DOI:

https://doi.org/10.32539/bsm.v4i4.170

Keywords:

Osteogenesis Imperfecta, Bisphosphonate, Compliance.

Abstract

BACKGROUND: Osteogenesis imperfecta (OI) is a genetic disease with clinical manifestations in patients' bones. This study aims to investigate the factors that influence the compliance of bisphosphonate in patients with OI.

METHODS: A cross-sectional analysis method was conducted and data were obtained from questionnaires answered by OI patients that received bisphosphonate. The data obtained were statistically analyzed using chi-square.

RESULTS: There were 121 OI patients, age range 0-5 years (62%). Almost all patients have insurance from national health (BPJS). In this study, the average treatment compliance was 81.7%, and patients were reported to have good medication compliance of ≥80% of the treatment cycle, which was shown in 65 patients (53.7%). However, there is a relationship between parent education and treatment compliance (P = 0.046).

DISCUSSION: It is a measurement of behavior related to treatment recommendations by medical professionals. On the contrary, the level of non-compliance patients with chronic disease to treatment is quite high.

CONCLUSION: Good treatment compliance describes when the patient performs ≥80% of its cycle. Factors affecting it are the condition of the patient and the location of health services. Therefore, there is a relationship between compliance with the number of treatment cycles.

Authors

  • Yoyos Ismiarto1*
  • Firdaus Ramli F2
  • Doddi Putra Pratama Sudjana2
  • Naufal Chairulfatah2
  • Wendy Yolanda Rossa2
  1. 1a:1:{s:5:"en_US";s:16:"RS Hasan Sadikin";}, Indonesia
  2. 2Resident of Orthopaedic and Traumatology, RS Hasan Sadikin, UNPAD, Bandung, Indonesia

Corresponding author Yoyos Ismiarto — yoyosismiartounpad@gmail.com

Article history

  1. Submitted
  2. Accepted
  3. Published

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Published

2020-10-03

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How to Cite

1.
Ismiarto Y, Firdaus Ramli F, Doddi Putra Pratama Sudjana, Naufal Chairulfatah, Wendy Yolanda Rossa. Factors Affecting Bisphosphonate Therapy Compliance In Patients With Osteogenesis Imperfecta . Bioscmed [Internet]. 2020 Oct. 3 [cited 2026 Aug. 14];4(4):55-9. Available from: https://bioscmed.com/index.php/bsm/article/view/170

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