Potential of Red Betel Leaf Extract (Piper crocatum) and Siwak (Salvadora persica) Against Staphylococcus Aureus Bacteria

Authors

  • Member Reni Purba Dentistry Study Program, Faculty of Dentistry, Universitas Prima Indonesia, Medan, Indonesia
  • Steven Wijaya Dentistry Study Program, Faculty of Dentistry, Universitas Prima Indonesia, Medan, Indonesia
  • Ananda Kasuma Dentistry Study Program, Faculty of Dentistry, Universitas Prima Indonesia, Medan, Indonesia

DOI:

https://doi.org/10.37275/bsm.v6i5.504

Keywords:

Piper Crocatum, Salvadora Persica, Staphylococcus Aureus, Antibacterial, Halitosis

Abstract

Background. One of the bacteria that cause oral cavity infection is Staphylococcus aureus.  This study aims to explore the antibacterial potential of red betel extract and siwak extract against Staphylococcus aureus bacteria, in vitro.

Methods. This research is an in vitro experimental study to assess the diameter of the inhibition zone of red betel leaf extract and siwak against Staphylococcus aureus. The extract was made from red betel leaf simplicia and siwak wood with a dose of 50% each. The bacterial suspension was made by taking one pure colony from a test tube. Data analysis was performed using SPSS version 25 software.

Results. Red betel leaf extract 50% showed the largest diameter of the inhibition zone, namely 9.1 ± 0.68 mm. Meanwhile, the siwak extract showed a smaller inhibition zone diameter of 7.9 ± 0.68 mm. One-way ANOVA analysis showed that there was a significant difference between the diameters of the inhibition zones of each test group.

Conclusion. Red betel leaf extracts are 50% greater in inhibiting the growth of Staphylococcus aureus than 50% siwak extract.

Authors

  • Member Reni Purba1*
  • Steven Wijaya1
  • Ananda Kasuma1
  1. 1Dentistry Study Program, Faculty of Dentistry, Universitas Prima Indonesia, Medan, Indonesia

Corresponding author Member Reni Purba — renimember1060@gmail.com

Article history

  1. Submitted
  2. Accepted
  3. Published

Downloads

Published

2022-03-11

Article metrics

878Abstract views
601PDF downloads

How to Cite

1.
Purba MR, Steven Wijaya, Ananda Kasuma. Potential of Red Betel Leaf Extract (Piper crocatum) and Siwak (Salvadora persica) Against Staphylococcus Aureus Bacteria. Bioscmed [Internet]. 2022 Mar. 11 [cited 2026 Aug. 2];6(5):1728-31. Available from: https://bioscmed.com/index.php/bsm/article/view/504

Most read articles by the same author(s)