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The pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The clinical manifestation of COVID-19 is broad, ranging from an asymptomatic carrier state to severe disease leading to the death penalty. There is also emerging evidence that kidneys are affected early in COVID-19. Proteinuria and haematuria have been reported in 44% and 26.7% on admission, respectively.   This literature review shows clinical manifestations of acute kidney injury (AKI) in a patient with COVID-19 infection. Literature reviews are carried out on various sources found on Google Scholar and Pubmed to search for articles, journal research, case reports, systematic reviews, meta-analyses, and textbooks. Various studies demonstrate the possibility of coronavirus infecting the kidney with several mechanisms such as cytokine storm syndrome (CSS), direct viral infection, and imbalance of renin-angiotensin-aldosterone (RAAS). Haematuria and proteinuria are associated with higher mortality and may signify aggressive disease early. Thus all patients should have a baseline urinalysis. There is a number of different causes of AKI in COVID-19, and some mechanisms by which COVID-19 affects kidneys remain unclear.


Acute kidney injury COVID-19 Proteinuria Hematuria

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How to Cite
Kartika, H., Novadian Suhaimi, Zulkhair Ali, Suprapti, Ian Effendi, Harun Hudari, Mega Permata, Nelda Aprilia Salim, & Eddy Yuristo. (2022). Recent Evidence on Acute Kidney Injury in COVID-19 Patients: A Narrative Review. Bioscientia Medicina : Journal of Biomedicine and Translational Research, 6(10), 2313-2321.