Human Papilloma Virus: Biomolecular Aspect

Authors

  • Patiyus Agustiansyah Department of Obstetric and Gynecology, Division Oncology of Gynecology, Faculty of Medicine, Universitas Sriwijaya / General Hospital Dr Moh. Hoesin, Palembang, Indonesia
  • Rizal Sanif Department of Obstetric and Gynecology, Division Oncology of Gynecology, Faculty of Medicine, Universitas Sriwijaya / General Hospital Dr Moh. Hoesin, Palembang, Indonesia
  • Siti Nurmaini Intelligent System Research Group, Universitas Sriwijaya, Palembang, Indonesia
  • Irfannuddin Department of Physiology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia
  • Legiran Department of Anatomy, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia

DOI:

https://doi.org/10.32539/bsm.v5i8.327

Keywords:

HPV, Cervical Cancer, Biomolecular

Abstract

HPV is a sexually transmitted virus, and high-risk HPV DNA was found in 99.7%
of cervical cancer specimens. Within 12 to 24 months of exposure to the virus,
90% of HPV infections disappear or become inactive. However, infection with high-
risk strains of HPV persist which then increases the risk of progression to cervical
cancer. The detection of precancerous lesions consists of various methods,
including pap smear (conventional or liquid-base cytology / LBC), visual
inspection of acetic acid (IVA), visual inspection of lugoliodine (VILI), and HPV DNA
test (genotyping / hybrid capture).

Authors

  • Patiyus Agustiansyah1*
  • Rizal Sanif1
  • Siti Nurmaini 2
  • Irfannuddin3
  • Legiran4
  1. 1Department of Obstetric and Gynecology, Division Oncology of Gynecology, Faculty of Medicine, Universitas Sriwijaya / General Hospital Dr Moh. Hoesin, Palembang, Indonesia
  2. 2Intelligent System Research Group, Universitas Sriwijaya, Palembang, Indonesia
  3. 3Department of Physiology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia
  4. 4Department of Anatomy, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia

Corresponding author Patiyus Agustiansyah — fatiyusagustiansyah@gmail.com

Article history

  1. Submitted
  2. Accepted
  3. Published

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Published

2021-04-05

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How to Cite

1.
Agustiansyah P, Rizal Sanif, Siti Nurmaini, Irfannuddin, Legiran. Human Papilloma Virus: Biomolecular Aspect. Bioscmed [Internet]. 2021 Apr. 5 [cited 2026 Aug. 12];5(8):709-16. Available from: https://bioscmed.com/index.php/bsm/article/view/327

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