Accreditation
SINTA 2Nationally Accredited Journal
Vol. 7 No. 4 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Articles
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Evans Syndrome in a Forty-Four Years Old Male Patient: A Case Report
Views: 707Downloads: 513Background: Evans syndrome (ES) is an autoimmune disease characterized by the presence of autoimmune hemolytic anemia (AIHA) and idiopathic thrombocytopenic purpura (ITP), together with unknown causes. ES disease is the least common, diagnosed in only 0.8% - 3.7% of all patients with AIHA or ITP. This study aimed to describe Evans syndrome in a 44-year-old male patient.
Case presentation: A 44-year-old male patient was reported with complaints of weakness and fatigue, red spots, a history of bleeding gums, a history of bleeding from the nose, and a history of red urination. A routine blood examination revealed mild anemia, reticulocytosis, and thrombocytopenia, and the peripheral blood showed polychromatic erythrocytes. Other laboratory examinations revealed an increase in LDH. The results of a positive Comb’s test and antibody screening examination showed the impression of warm-type AIHA. The diagnosis of Evans syndrome in this patient was confirmed by the presence of AIHA and ITP, which co-occur and are primarily due to unknown causes.
Conclusion: ES is a rare disorder and a diagnosis of exclusion. The diagnosis of ES was established by the presence of signs and symptoms of AIHA and ITP accompanied by a positive direct antiglobulin test with no other etiology found.
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Increasing Public Knowledge About Sedentary Activities Through Counseling at SMPIT Zain Al-Muttaqin, Palembang, Indonesia
Views: 637Downloads: 366Background: Sedentary activities are activities that require very low energy expenditure, such as sitting or lying down while watching television, playing electronic games, and reading which can have negative health effects. This study aimed to describe the comparison of participants' knowledge before and after counseling about sedentary activities.
Methods: An experimental study with one group pre-test and post-test design was conducted on 22 students of SMPIT Zain Al-Muttaqin Palembang. Data were analyzed using the Wilcoxon test.
Results: There were 63.6% of participants' knowledge was in the poor category before counseling, and after counseling, the participant's knowledge increased by 59.1% in the good category. From the Wilcoxon test analysis, the result is the value of Sig. (2-tailed) of 0.000 < 0.05.
Conclusion: Student knowledge is increased about activities sedentary after counseling, and there is a significant difference in the results of sedentary lifestyle counseling based on data pre-test and post-test (P<0,05).
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Comorbidities of Gestational Diabetes Mellitus and Urinary Tract Infection: A Case Report
Views: 2,051Downloads: 1,373Background: Gestational diabetes mellitus (GDM) is defined as a condition of glucose intolerance that is found during pregnancy. In pregnant women, urinary tract infection (UTI) is one of the most common bacterial infections that can be found. The infection can be worsened by diabetes as it was shown that the risk of UTI in pregnant women with diabetes (27.6%) is higher than those without diabetes (3%-10.1%). This study aimed to present a case of gestational diabetes mellitus and urinary tract infection.
Case presentation: A pregnant woman aged 38 years old with a 15-16 weeks gestational age was admitted with gestational diabetes mellitus and urinary tract infection. The patient was treated with an intravenous insulin drip and antibiotic. The patient was discharged after there was a clinical improvement.
Conclusion: There are many risk factors that can contribute to the development of UTI in pregnant women, with one of those being inadequate glycemic control. The treatment of UTI in pregnant women with GDM is generally the same as in those without GDM.
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The Relationship between Gender and Presbycusis at Mandalika Elderly Social Center, West Nusa Tenggara, Indonesia
Views: 637Downloads: 685Background: Presbycusis is a type of hearing loss with sensorineural deafness due to the degeneration of the hearing organs. Gender is said to have an influence on the occurrence of presbycusis. The presbycusis is influenced by differences in activity routines carried out by women and men and differences in the anatomical shape of the auricles between men and women. The study aimed to identify the relationship between gender and presbycusis at the Mandalika Elderly Social Center, West Nusa Tenggara, Indonesia.
Methods: The study design was observational analytic with cross sectional approach and purposive sampling technique. There were 50 research respondents who met the inclusion and exclusion criteria. The research was conducted at the Mandalika Elderly Social Center, West Nusa Tenggara, Indonesia. The data obtained were analyzed univariately and bivariate with the Chi-square test using SPSS software version 23.0.
Results: It was obtained that the demographic description of the research respondents obtained the majority of respondents aged 60-74 years (66%), female (66%), ungraduated (90%), and unemployed (90%). There was no relationship between gender and presbycusis at the Mandalika Elderly Social Center, West Nusa Tenggara Indonesia, p> 0,05.
Conclusion: There was no relationship between gender and presbycusis at the Mandalika Elderly Social Center, West Nusa Tenggara, Indonesia.
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The Relationship between Clinical Appearance and Albumin Levels in Pulmonary Tuberculosis (TB) Patients at Dr. M. Djamil General Hospital, Padang, Indonesia
Views: 1,555Downloads: 682Background: Pulmonary TB is strongly associated with malnutrition. Malnutrition is often found in pulmonary TB patients, especially hospitalized patients, and can worsen the treatment and recovery outcomes of pulmonary TB patients. Pulmonary TB patients can experience a significant decrease in albumin levels, and albumin is the largest protein in blood plasma. This study aimed to determine the relationship between the patient's clinical appearance and albumin levels in pulmonary tuberculosis patients at Dr. M. Djamil General Hospital, Padang, Indonesia.
Methods: This study was an analytic observational study with a retrospective cohort approach. A total of 177 research subjects participate in this study. Observations on sociodemographic data, clinical data, and laboratory data were carried out in this study. Data analysis was carried out using SPSS version 25 univariate and bivariate.
Results: Clinical appearance of pulmonary TB patients treated in the pulmonary ward isolation room at Dr. M. Djamil General Hospital, Padang, Indonesia, which is significantly related to albumin levels is BMI (underweight and normal) and complications pneumothorax (p<0.05); while other clinical appearances such as onset and complications of coughing up blood, pleural effusion, hydropneumothorax, and without complications not related to albumin levels (p>0.05).
Conclusion: BMI (underweight and normal) and complications pneumothorax is a clinical picture related to albumin levels in pulmonary tuberculosis patients at Dr. M. Djamil General Hospital, Padang, Indonesia.
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Effect of Ramadan Fasting on DNA Repair, Immune System, Inflammation and Cognitive Function in Chronic Kidney Disease Patients: A Systematic Literature Review
Views: 1,030Downloads: 769Background: There have been many studies that say Ramadan fasting has a positive effect on reducing BMI, blood sugar, inflammatory factors, and DNA Repair. However, there are still no guidelines for fasting in patients with chronic kidney disease (CKD) both nationally and internationally. This study aimed to conduct a review to explore the effects of Ramadan fasting against chronic kidney disease, specifically on DNA repair, Immune System, Inflammation, and Cognitive Function in patients with chronic kidney disease.
Methods: This study is a systematic literature review (SLR) with sources obtained from various reputable journal databases such as PubMed, Cochrane Library, EBSCO, and Elsevier using relevant keywords. The selected articles have passed the inclusion and exclusion criteria. A total of 39 articles that discuss fasting were obtained from Ramadan in chronic kidney disease patients on metabolic response and inflammatory markers in the body.
Results: Ramadan fasting has a positive effect on the response to anti-inflammatory, expression of protective genes, markers of kidney and liver function, protective proteome, and oxidative stress.
Conclusion: Ramadan fasting may provide a short-term protective effect against levels of systemic inflammation.
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Effect of Oxytocin Massage on Uterine Involution in Postpartum Mothers at Rengasdengklok Health Center, Karawang Regency
Views: 1,223Downloads: 1,356Background. After giving birth, the uterus will normally experience involution, which is the process of shrinking and returning to its pre-pregnancy size and shape. The process of involution involves uterine contractions, decreased blood flow, and the expulsion of unnecessary tissue. However, in case of failed uterine involution, the uterus cannot return to its normal size and shape in a timely manner, and leads to bleeding. This study aimed to determine the effect of oxytocin massage on uterine involution of postpartum mothers at the Rengasdengklok Health Center, Karawang Regency, Indonesia.
Methods. This study was an experimental study, where as many as 30 research subjects participated in this study. Data analysis was performed bivariate to assess the effect of oxytocin massage on uterine involution.
Results. The results of the study showed that the control group had a slower process of uterine involution compared to the intervention group, p-value 0.003 (p<0.05).
Conclusion. It can be concluded that there is an influence between oxytocin massage and the uterine involution process.
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The Effect of Giving Dark Chocolate on Reducing Menstrual Pain in Primary Dysmenorrhoea in Employees of Cabangbungin General Hospital, Bekasi Regency in 2023
Views: 7,258Downloads: 742Background. Dark chocolate can be used as an alternative to overcome pain during menstruation time because it contains many benefits in the health sector. This study aimed to determine the effect of giving dark chocolate on reducing dysmenorrhea menstrual pain in female employees of the Cabangbungin General Hospital, Bekasi Regency, in 2023.
Methods. This study was an experimental study of 32 research subjects. Data analysis was carried out univariate and bivariate using SPSS version 25.
Results. Statistical test results used test paired sample t-test obtained ρ value = 0.000, with a value of α = 0.05 (ρ <α), indicating that there is an effect of giving dark chocolate to reducing dysmenorrhea menstrual pain.
Conclusion. There was an effect of giving dark chocolate to reducing dysmenorrhea menstrual pain in female employees of the Cabangbungin General Hospital, Bekasi Regency, in 2023.
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The Effect of Unripe Papaya Consumption on the Smooth Production of Breast Milk in Ciandam Village, Mande District, Cianjur, Indonesia
Views: 4,122Downloads: 3,266Background. Consumption of unripe papaya is one of the local wisdom which is believed to be useful in increasing the breast milk production of breastfeeding mothers. Hereditary unripe papaya has been consumed in public areas to increase milk production. This study is one of the first studies to provide scientific evidence of the effects of the unripe papaya on breast milk production in Ciandam Village, Mande District, Cianjur, Indonesia. Methods. This study was an experimental study, where as many as 30 subjects participated in this study. Data analysis was carried out using SPSS 25 in a bivariate manner to determine the effect of unripe papaya consumption on breast milk production. Results. After consumption of fruit papaya on the first day, there was increased production of Breast milk in the intervention group compared to before consumption of unripe papaya p=0.02 (p<0.05). Likewise, after the consumption of unripe papaya on the second to the seventh day, an increase in milk production was found in the intervention group compared to before the consumption of unripe papaya, p < 0.05. Conclusion. There is an influence of unripe papaya consumption on the smooth breast milk of breastfeeding mothers in Ciandam village, Mande District, Cianjur, Indonesia.
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Clinical Overview and Treatment of Hypokalemia in Pediatric Patients: A Narrative Literature Review
Views: 2,351Downloads: 1,132Hypokalemia is a condition in which the blood potassium levels are below the normal range, which is typically between 3.5 and 5.0 mEq/L. Potassium is an essential electrolyte that plays a critical role in many physiological processes in the body, including nerve and muscle function, heart rhythm, and acid-base balance. This literature review aimed to describe the clinical and current management aspects of hypokalemia in pediatric patients. The pathophysiology of hypokalemia involves a disturbance in the balance of potassium in the body, which can occur due to several mechanisms, including reduced intake of potassium-rich foods, increased loss of potassium, and redistribution of potassium. In children, clinical symptoms of hypokalemia may include weakness and fatigue, abdominal discomfort, cardiac symptoms, respiratory symptoms, neurological symptoms, polyuria, and renal symptoms. There are several diseases and conditions that can cause hypokalemia in children, including renal tubular acidosis, prolonged diarrhea, cystic fibrosis, hyperaldosteronism, malnutrition, medication, type 1 Bartter syndrome, type 2 Bartter syndrome, and Liddle syndrome. Some options for hypokalemia treatment are potassium supplements, a potassium-rich diet, intravenous potassium, and treating underlying conditions. In conclusion, hypokalemia is an overview of the underlying disease and requires immediate management. Understanding the pathophysiology of hypokalemia will increase the accuracy of diagnosis and accelerate hypokalemia intervention in children, as well as prevent complications due to hypokalemia.
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The Effect of Birth Ball Exercise on the Progress of Labor During the First Active Phase at PONED (Basic Emergence Neonatal Obstetric Services) UPTD DTP Pedes Health Center, Karawang Regency, Indonesia
Views: 617Downloads: 395Background.Prolonged parturition or labor that lasts longer than usual can increase the risk of complications and the potential for maternal death. The birth ball exercise, also known as the birth ball exercise or the pregnancy ball exercise, can help harness the influence of gravity to induce labor progress. This study aimed to assess the effect of birth ball exercises on the progress of labor during the first active phase at the PONED UPTD DTP Pedes Health Center, Karawang Regency, Indonesia. Methods.This study is an experimental study, where as many as 30 research subjects participated in this study. Analysis of the progress of labor was carried out using SPSS software in a univariate and bivariate manner. Results. The results of the study showed that the birth ball exercise had an effect on the progress of labor with a p-value = 0.002 (p <0.05). Conclusion, there is an influence of birth ball exercises on the progress of labor at PONED UPTD DTP Pedes Health Center, Karawang Regency, Indonesia.
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The Effect of Giving Cucumber Masks against Melasma in Acceptors of Combination Injection Contraception Users at the Independent Midwife Practice in Bungursari, Purwakarta, Indonesia
Views: 1,262Downloads: 1,481Background. Cucumber is one of the natural ingredients that has been widely used traditionally to maintain facial skin health. Cucumber is rich in antioxidants which have the potential to suppress the inflammatory process that arises due to hormonal imbalances in melasma sufferers due to the use of injectable contraception. This study aimed to determine the effect of using a cucumber mask on the incidence of melasma in acceptors injection contraception users at the independent midwife practice in Bungursari, Purwakarta, Indonesia.
Methods. This study was an experimental study in which a total of 30 research subjects participated in this study. Data analysis was carried out using SPSS 25 software in a bivariate manner to determine the effect of using cucumber masks on melasma.
Results. After using the cucumber mask on the first day, there was an improvement in melasma in the intervention group compared to before using the cucumber mask, p=0.02 (p<0.05). Likewise, after using the cucumber mask on the second to the seventh day, there was an improvement in melasma in the intervention group compared to before using the cucumber mask, p <0.05.
Conclusion. There is an effect of using a cucumber mask on melasma in acceptors of injection contraception users at the independent midwife practice in Bungursari, Purwakarta, Indonesia.
