Impact of Open-Angle Glaucoma Severity on Vision-Related Quality of Life: A Cross-Sectional Study in a Single Center in Indonesia

Authors

  • Rino Agustian Praja Department of Ophthalmology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia
  • Andrini Ariesti Department of Ophthalmology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia
  • Hendriati Department of Ophthalmology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia
  • Muhammad Hidayat Department of Ophthalmology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia
  • Irayanti Department of Ophthalmology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia
  • Julita Department of Ophthalmology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia

DOI:

https://doi.org/10.37275/bsm.v9i1.1171

Keywords:

Glaucoma, NEI-VFQ 25, Primary open-angle glaucoma, Quality of life, Severity

Abstract

Background: Glaucoma is a progressive optic neuropathy characterized by the gradual loss of retinal ganglion cells (RGCs) and their axons, leading to irreversible visual field loss. This study aimed to investigate the relationship between the severity of primary open-angle glaucoma (POAG) and vision-related quality of life (VRQoL) in a single center in Indonesia.

Methods: A cross-sectional study was conducted at the eye polyclinic of Dr. M. Djamil General Hospital, Padang, Indonesia, from June to August 2024. A total of 54 patients with POAG were included and categorized into mild, moderate, and severe groups based on their cup-to-disc ratio and visual field index (VFI). VRQoL was assessed using the Indonesian version of the National Eye Institute Visual Function Questionnaire (NEI-VFQ 25).

Results: The mean VRQoL score was significantly lower in the severe group (60.63 ± 13.04) compared to the moderate (81.79 ± 10.42) and mild (85.04 ± 10.52) groups (p = 0.000). A strong negative correlation was observed between glaucoma severity and VRQoL (r = -0.667, p = 0.000). The social functioning subscale showed the strongest correlation with severity (r = -0.573, p = 0.000).

Conclusion: The severity of POAG significantly impacts VRQoL, with more severe disease associated with lower QoL scores. The social functioning domain appears to be particularly affected. These findings underscore the importance of comprehensive glaucoma management that addresses not only clinical parameters but also the patient's overall quality of life.

Authors

  • Rino Agustian Praja1*
  • Andrini Ariesti1
  • Hendriati1
  • Muhammad Hidayat1
  • Irayanti1
  • Julita1
  1. 1Department of Ophthalmology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia

Corresponding author Rino Agustian Praja — agustian506@gmail.com

Article history

  1. Submitted
  2. Accepted
  3. Published

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Published

2024-10-30

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How to Cite

1.
Rino Agustian Praja, Andrini Ariesti, Hendriati, Muhammad Hidayat, Irayanti, Julita. Impact of Open-Angle Glaucoma Severity on Vision-Related Quality of Life: A Cross-Sectional Study in a Single Center in Indonesia. Bioscmed [Internet]. 2024 Oct. 30 [cited 2026 Aug. 12];9(1):193-205. Available from: https://bioscmed.com/index.php/bsm/article/view/1171

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