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Recognition of pain depends upon intact pathways from pain receptors to the
thalamus and cerebral cortex, as well as functional cerebral cortex and subcortical
structures. Thus any means that renders the cerebral cortex nonfunctional, such
as hypoxia or drug depression, prevents pain. When this happens, stimuli that
evoke motor nerve reflexes that may be painful to the conscious animal are not
painful in the unconscious animal. Equally painful stimuli administered to
animals chemically paralyzed by curare or succinylcholine will not evoke a motor
reflex simply because of paralysis, but will cause pain because of the conscious
state. Hence, it is possible that unconscious animals may feel no pain but respond
to certain stimuli, and paralyzed animals may feel pain but cannot respond.


Anasthesia Pain Protocol

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How to Cite
Hidayat, R., & Patricia Wulandari. (2021). Protocol for Anesthesia Animal Model in Biomedical Study. Bioscientia Medicina : Journal of Biomedicine and Translational Research, 5(3), 522-526.

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