Is It a Tumor or Not? A Case of Focal Segmental Glomerulosclerosis Secondary to Type 2 Diabetes with a Concomitant Renal Pseudotumor

Authors

  • Rery TF Yuniarti Subspecialized Residency Training Student of Nephrology, Department of Internal Medicine, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  • Ian Effendi Department of Internal Medicine, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  • Zulkhair Ali Department of Internal Medicine, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  • Novadian Department of Internal Medicine, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  • Suprapti Department of Internal Medicine, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  • Elfiani Subspecialized Residency Training Student of Nephrology, Department of Internal Medicine, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  • Novandra AP Subspecialized Residency Training Student of Nephrology, Department of Internal Medicine, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  • Dila Siti Hamidah Department of Radiology, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  • Fadil Pramudhya Husein Department of Urology, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  • Ika Kartika Edi P Department of Anatomical Pathology, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia

DOI:

https://doi.org/10.37275/bsm.v8i12.1154

Keywords:

Case report, Focal segmental glomerulosclerosis, Kidney biopsy, Renal pseudotumor, Type 2 diabetes

Abstract

Background: Focal segmental glomerulosclerosis (FSGS) is a histologic pattern of glomerular injury that can be primary or secondary to various conditions, including obesity, diabetes, and hypertension. Renal masses, often detected incidentally, can be benign or malignant, with renal cell carcinoma (RCC) being the most common. This case report presents a patient with FSGS secondary to type 2 diabetes and a concomitant renal pseudotumor, initially suspected to be RCC.

Case presentation: A 60-year-old woman presented with weakness, fever, and weight loss. Imaging revealed a renal mass, initially suspected to be RCC. A kidney biopsy revealed FSGS, and further evaluation confirmed type 2 diabetes. After controlling her diabetes and hypertension, the renal mass regressed, suggesting a pseudotumor.

Conclusion: This case highlights the importance of considering pseudotumors in the differential diagnosis of renal masses, especially in patients with comorbidities such as diabetes. A kidney biopsy can help avoid unnecessary invasive procedures like nephrectomy.

Authors

  • Rery TF Yuniarti1*
  • Ian Effendi2
  • Zulkhair Ali2
  • Novadian2
  • Suprapti2
  • Elfiani1
  • Novandra AP1
  • Dila Siti Hamidah3
  • Fadil Pramudhya Husein4
  • Ika Kartika Edi P5
  1. 1Subspecialized Residency Training Student of Nephrology, Department of Internal Medicine, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  2. 2Department of Internal Medicine, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  3. 3Department of Radiology, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  4. 4Department of Urology, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
  5. 5Department of Anatomical Pathology, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia

Corresponding author Rery TF Yuniarti — rerysppd@gmail.com

Article history

  1. Submitted
  2. Accepted
  3. Published

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Published

2024-10-07

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How to Cite

1.
Rery TF Yuniarti, Ian Effendi, Zulkhair Ali, Novadian, Suprapti, Elfiani, et al. Is It a Tumor or Not? A Case of Focal Segmental Glomerulosclerosis Secondary to Type 2 Diabetes with a Concomitant Renal Pseudotumor. Bioscmed [Internet]. 2024 Oct. 7 [cited 2026 Aug. 16];8(12):5801-13. Available from: https://bioscmed.com/index.php/bsm/article/view/1154

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